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Symbol
Name
ID
Cdkn1a
cyclin dependent kinase inhibitor 1A
MGI:104556
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
impaired macrophage chemotaxis
increased T cell proliferation
abnormal thymus physiology
enlarged spleen
increased spleen weight
spleen hyperplasia
increased B cell number
increased memory T cell number
decreased monocyte cell number
abnormal CD4-positive, alpha beta T cell morphology
abnormal spleen morphology
increased IgG1 level
enlarged lymph nodes
lymph node hyperplasia
enlarged cervical lymph nodes
abnormal self tolerance
decreased susceptibility to induced arthritis
increased autoantibody level
increased anti-nuclear antigen antibody level
increased anti-double stranded DNA antibody level
increased anti-histone antibody level
increased anti-single stranded DNA antibody level
glomerulonephritis
Availability Mouse Genotype
Cdkn1atm1.1(KOMP)Vlcg/Cdkn1atm1.1(KOMP)Vlcg
Cdkn1atm1Led/Cdkn1atm1Led
Cdkn1atm1Tyj/Cdkn1atm1Tyj *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory